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Anticonvulsant Screening Program
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Standard Anti-Ictal Screening
Models of Pharmacoresistance
Identification/Differentiation
Screening for Related Indications
Special Capabilities and Studies under Development
Experimental Animals and Animal Care
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PANAChE DATABASE Line  
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Substance Information
Structure

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PANAChE ID
Molecular Weight
Molecular Formula
Smiles
Chemical Class
Therapeutic Class
CAS No
Stereotype
Salt
PubChem ID
Bioactivity
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Maximum Electroshock Model Subcutaneous Metrazol Model Toxicity (rotorod-mouse,ataxia-rat)
Mouse i.p. Screen
Mouse i.p. ED50
Mouse p.o. ED50
Rat p.o. Screen
Rat p.o. ED50
Rat i.p. Screen
Rat.i.p. ED50
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Kindled Rat/Mouse
Rat Hippocampal Screen Mouse Corneal
Rat Hippocampal Toxicity Rat Hippocampal Afterdischarge Threshold
Rat Hippocampal ED50 Rat LTG-Resistant Amygdala
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Subcutaneous Bicuculline Model Subcutaneous Picrotoxin Model
Mouse i.p.
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Threshold Electro Convulsive Model
Threshold Tonic Extension
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Pilocarpine Induced Status Prevention (PISP)
0 min Screen
0 min ED50
30 min Screen
30 min ED50
EEG Study
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Neuroprotection - Hippocampal slice culture
Kainate
NMDA
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Spatial Learning & Memory
Morris Water Maze
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6Hz Model
Screen
ED50
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Pain
Mouse Formalin
Rat Sciatic Ligation
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Electrophysiology
Kainate/Na+/GABA/NMDA
Spontaneous Burst
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i.v. Metrazol Infusion Model
Time to first twitch/clonus  
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Frings Audiogenic Sezisure Model
ED50
 
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Test Report in PDF format
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Solvent Code Description
ACN Acetonitrile
DMF Dimethyl Formamide
DMSO Dimethyl Sulfoxide
HPC Hydroxypropyl Cellulose
MC Methyl Cellulose
MEOH Methanol
MP 1-methyl-2-pyrrolidone (MP)
OTH Other
PEG Polyethylene Glycol
SAL Saline
WAT Water
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Solvent Prep Code Description
HT Heat
M&P Mortar & pestle
SB sonabath
TW Tween (will include a number which indicates concentration, ie/ TW20 or TW80)
TT Test tube

Note: PANAChE ID, ADD ID and ASP ID are the same.
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** Test has been done more than once. The data displayed represent information collected from the most recent experiment.
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Test Description
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* Public Access to Neuroactive & Anticonvulsant CHemical Evaluations (PANAChE) database
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