Publications relating to ETSP / ASP programs
The list of references below is a result of an extensive literature search to identify publications that acknowledged the ETSP / ASP program, published program data or described the programs
References
Dimmock JR, Puthucode RN, Smith JM, Hetherington M, Quail JW, Pugazhenthi U, Lechler T, Stables JP. (Aryloxy)aryl semicarbazones and related compounds: a novel class of anticonvulsant agents possessing high activity in the maximal electroshock screen. J Med Chem. 1996:39;3984–3997. PMID: 8831764
Gunia-Krzyżak A, Żesławska E, Nitek W, Popiół J, Marona H. Anticonvulsant Activity of Enantiomeric N-trans -Cinnamoyl Derivatives of 2-Aminopropan-1-ols and 2-Aminobutan-1-ols: Anticonvulsant Activity of Enantiomeric Cinnamamide Derivatives. Chirality. 2016:28;482–488. PMID: 27121961
Kuder K, Łażewska D, Latacz G, Schwed JS, Karcz T, Stark H, Karolak-Wojciechowska J, Kieć-Kononowicz K. Chlorophenoxy aminoalkyl derivatives as histamine H(3)R ligands and antiseizure agents. Bioorgan Med Chem. 2016;24:53–72. PMID: 26690914
Obniska J, Kaminski K, Skrzynska D, Pichor J. Synthesis and anticonvulsant activity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 3-phenyl-pyrrolidine-2,5-dione. Eur J Med Chem. 2009:44;2224–2233. PMID: 18603334
Obniska J, Dzierzawska-Majewska A, Zagorska A, Zajdel P, Karolak-Wojciechowska J. Synthesis, physicochemical and anticonvulsant properties of N-benzyl and N-aminophenyl derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione. Part I. Farmaco. 2005:60;529-539. PMID: 15950973
Paruszewski R, Strupińska M, Stables JP, Swiader M, Czuczwar S, Kleinrok Z, Turski W. Amino Acid Derivatives with Anticonvulsant Activity. Chem Pharm Bull (Tokyo). 2001:49;629–631. PMID: 11383620
Shimshoni JA, Bialer M, Wlodarczyk B, Finnell RH, Yagen B. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid. J Med Chem. 2007:50;6419–6427 PMID: 17994680
Tripathi L, Singh R, Stables JP. Design & synthesis of N′-[substituted] pyridine-4-carbohydrazides as potential anticonvulsant agents. Eur J Med Chem. 2011:46;509–518. PMID: 21167624
Ucar H, Van derpoorten K, Cacciaguerra S, Spampinato S, Stables JP, Depovere P, Isa M, Masereel B, Delarge J, Poupaert JH. Synthesis and anticonvulsant activity of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives. J Med Chem. 1998:41;1138-1145. PMID: 9544213
Waszkielewicz, A. M. et al. Design, Synthesis and Anticonvulsant Activity of Some Derivatives of Xanthone with Aminoalkanol Moieties. Chem Biol Drug Des. 2017:89;339–352. PMID: 27543433
White HS, Alex AB, Pollock A, Hen N, Shekh-Ahmad T, Wilcox KS, McDonough JH, Stables JP, Kaufmann D, Yagen B, Bialer M. A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage. Epilepsia. 2012:53;134–146. PMID: 22150444
John R. Carson, Richard J. Carmosin, Philip M. Pitis, Jeffry L. Vaught, Harold R. Almond, James P. Stables, Harold H. Wolf, Ewart A. Swinyard and H. Steve White. Aroyl(aminoacyl)pyrroles, a New Class of Anticonvulsant Agents. J. Med. Chem. 1997; 40: 1578–1584. PMID: 9171868
A.M. Waszkielewicz, A. Gunia-Krzyżak, B. Powroźnik, K. Słoczyńska, E. Pękala, M. Walczak, M. Bednarski, E. Żesławska, W. Nitek, H. Marona. Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents. Bioorganic & Medicinal Chemistry, 2016; 24:1793-1810. PMID: 26988801
Anna M. Waszkielewicz, Karolina Słoczyńska, Elżbieta Pękala, Paweł Żmudzki, Agata Siwek, Anna Gryboś, Henryk Marona. Design, synthesis, and anticonvulsant activity of some derivatives of xanthone with aminoalkanol moieties. Chemical Biology & Drug Design, 2017; 89 (3): 339-352. PMID: 27543433
Hafiz Mawasi, David Bibi , Meir Bialer. Design and comparative anticonvulsant activity assessment of CNS-active alkyl-carbamoyl imidazole derivatives. Bioorg Med Chem, 2016; 24 (18): 4246-4253. PMID: 27469980
Agnieszka Gunia-Krzyżak, Ewa Żesławska, Wojciech Nitek, Justyna Popiół, Henryk Marona. Anticonvulsant Activity of Enantiomeric N-trans-Cinnamoyl Derivatives of 2-Aminopropan-1-ols and 2-Aminobutan-1-ols. Chirality, 2016; 28 (6): 482-488. PMID: 27121961
Nichole Coleman, Hai M Nguyen, Zhengyu Cao, Brandon M Brown, David Paul Jenkins, Dorota Zolkowska, Yi-Je Chen, Brian S Tanaka, Alan L Goldin, Michael A Rogawski, Isaac N Pessah, Heike Wulff. The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant. Neurotherapeutics, 2015; 12 (1): 234-249. PMID: 25256961